| TITLE |
Amyotrophic Lateral Sclerosis |
| ABSTRACT |
The gradual loss of motor neurons in the brain and spinal cord is a hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS). Current ALS management, from diagnosis to prognosis, is still unsatisfactory despite much study. Frontotemporal dementia (FTD) and ALS share pathological characteristics, and many individuals exhibit traits from both conditions. The disease is now known to be caused by a wide variety of genes and pathophysiological mechanisms, and in order to develop successful treatments, it will be essential to comprehend this heterogeneity. Although a fraction of patients has familial disease and contain mutations in genes that play different roles in neuronal function, the processes underlying the development of ALS in the majority of patients are not well known. We discuss every facet of ALS, including its epidemiology, risk factors, causes, clinical manifestations, diagnostic procedures, and treatment. The reader will benefit from having access to a wide variety of disease-related information as a result. |
| AUTHOR |
Hema Rani, Ruhit Ashraf, Aman Kaur
Associate Professor, S. Lal Singh Memorial College of Pharmacy, Desh Bhagat University, Punjab, India
Assistant Professor, S. Lal Singh Memorial College of Pharmacy, Desh Bhagat University, Punjab, India
Pursuing B. Pharmacy, S. Lal Singh Memorial College of Pharmacy, Desh Bhagat University, Punjab, India.
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| PUBLICATION DATE |
2025-11-13 22:27:07 |
| VOLUME |
13 |
| ISSUE |
4 |
| DOI |
DOI: 10.15662/IJMSERH.2025.1304012 |
| PDF |
pdf/2025/10/12_Amyotrophic Lateral Sclerosis.pdf |
| KEYWORDS |
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